โค๏ธ Heart Health ยท Cardiovascular Disease

Detect plaque deposition in your arteries before it happens.

With our machine learning algorithm, identify specific molecular pathways leading to plaque deposition in your arteries and triggering onset of cardiovascular diseases years before conventional diagnostics can detect it.

India’s Cardiovascular Crisis
#1 cause
Cardiovascular disease is the leading cause of death in India โ€” responsible for 1 in 4 deaths
80%
Specificity on our cardiovascular disease prediction model โ€” validated on 15Bn+ molecular data sets
75%
Sensitivity on our cardiovascular disease prediction model โ€” validated on 15Bn+ molecular data sets
Based on WHO India Report 2023 & Genefitletics clinical studies
Go beyond lipid panels & cholesterol tests

What is VASCOMATH?

Go beyond cholesterol & lipid panels to assess cardiovascular health at molecular level.

Our full-body biochemistry solution measures and quantifies specific microbial molecular signatures that are triggering the onset of cardiovascular diseases โ€” identifying the inflammatory and metabolic pathways causing plaque deposition in your arteries, long before a cardiac event.

Conventional heart health tests measure cholesterol, LDL, triglycerides or blood pressure. VASCOMATH goes further โ€” deciphering the role of your oral and gut microbiome in the onset of cardiovascular disease, and delivering a complete molecular picture of your heart & metabolic health.

The connection between gum disease and cardiovascular disease is one of the most clinically significant and underdiagnosed relationships in medicine. VASCOMATH measures the oral microbial pathways driving this systemic inflammatory cascade โ€” and delivers targeted interventions to reverse it.

VASCOMATH Model Oralโ€“Heart Connection TMAO & LPS Pathways Stage 0โ€“1 Detection
Cardiovascular disease molecular prediction โ€” Genefitletics
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Improve cardiovascular health the microbiome way
Balance your oral and gut microbiome to suppress pro-inflammatory molecular pathways driving plaque deposition and arterial dysfunction.
๐Ÿฆท
Discover the gum diseaseโ€“heart disease link
Measure the oral microbial pathways connecting periodontal disease to cardiovascular risk โ€” a clinically validated but routinely overlooked connection.
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Precision heart health interventions
Receive a customised protocol of foods, supplements, biotics and oral hygiene interventions โ€” mapped to your specific cardiovascular molecular pathways.

ORAHYG PRO โ€” Full Body Biochemistry Solution

Our unique test measures your microbiome & cellular functions to predict & prevent cardiovascular disease.

Our full-body biochemistry solution empowers you and your healthcare practitioners with deeper insight about your oral and gut microbiome at molecular level โ€” identifying hard-to-detect early molecular signatures for cardiovascular disease and delivering the most comprehensive heart health insights available.

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Data Collection & Analysis
โ–พ
  • Easy at-home saliva sample collection
  • Detailed view of your overall health at molecular level via 70+ biological pathway scores & 10 whole-body scores
  • Decode the underlying molecular cause of cardiovascular disease onset
  • Access to a computational biology platform for your healthcare practitioners
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Disease Prediction
โ–พ
  • Predict onset of Cardiovascular Disease
  • Identify plaque-forming molecular pathways before arterial damage occurs โ€” making ECG & lipid panels redundant for early detection
  • Detect molecular dysregulation before conventional diagnostics can detect it
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Disease Modifiable Interventions
โ–พ
  • Molecular data-driven precision nutrition, supplement, biotics & oral hygiene interventions
  • Support health functions tied to blood pressure regulation, gut health, metabolic health & more
  • Real-time monitoring at regular intervals to revise interventions aligned with your current biochemistry
๐Ÿ–ฅ๏ธ
Technology Tools
โ–พ
  • Efficacy mapping via clinically validated questionnaires to assess the impact of the nutritional therapeutics programme on health outcomes
  • Personalised nutrition planner eliminating the need for a nutritionist or health coach
Annual Subscription
ORAHYG PRO
Full Body Biochemistry ยท CVD Prediction ยท Heart Health
Sample Saliva
Health Scores 72
Results In 4 weeks
Prediction Models 4
CVD Sensitivity 75%
Age Eligibility 9+ years

At-Home Testing Process

Four simple steps to your cardiovascular health report.

No clinic visit. No blood draws. A simple at-home saliva sample and 4 weeks to a complete molecular picture of your cardiovascular disease risk.

1
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Sign up & receive your kit
Subscribe to ORAHYG PRO and your at-home saliva sample collection kit is shipped to your registered address.
2
๐Ÿงซ
Collect your saliva sample
Follow the included instructions to collect your saliva sample. We arrange pick-up within 24โ€“36 hours of your confirmation.
3
๐Ÿ“‹
Complete your phenotype form
Fill your scientifically designed digital phenotype form capturing your current health conditions, allergies and lifestyle.
4
๐Ÿ“Š
Receive your insights & recommendations
Access your complete cardiovascular risk scores, molecular pathway insights and personalised precision recommendations in 4 weeks.

What’s Covered

Your complete cardiovascular molecular picture.

Get a digital bioatlas of your biology at molecular level with Asia’s first and only system biology platform analysing downstream biochemical functions of your oral and gut microbiome combined with cellular health.

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Full Body Molecular Insights
Gut + Oral Microbiome + Cellular Health

70+ personalised molecular health insights and scores that reveal your cardiovascular risk at molecular level โ€” identifying early molecular signatures for heart disease and forming the basis of precision nutrition as medicine. Track improvements in your pathway scores at re-sequencing after 12 months.

๐Ÿ’ฏ
Whole Body Scores
10 systemic health dimensions
  • Gut Health
  • Oral Health
  • Skin Health
  • Heart & Metabolic Health
  • Brain & Cognitive Health
  • Stress Response
  • Immune System Health
  • Hormonal Health
  • Inflammation Response
  • Energy Efficiency
๐Ÿฆท
Oral Pathway Scores
25+ oral microbiome pathways
  • Oral H2S
  • Oral Methyl Mercaptan Production
  • Oral Polyamines Production
  • Oral Ammonia Production
  • Oral Urease Pathways
  • Oral Butyrate Production
  • Oral Inflammatory Pathways
  • Oral Nitric Oxide Production
  • Oral Cavities Promoting Pathways
& 25 more pathway scores
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Gut Pathway Scores
19+ gut microbiome pathways
  • Butyrate Production
  • Oxalate Metabolism
  • Histamine Overproduction
  • Antioxidant Score
  • LPS Production
  • TMAO Production
& 19 more pathway scores
โšก
Cellular Pathway Scores
Mitochondrial & cellular health
  • Cellular Senescence
  • Cellular Stress
  • Energy Efficiency
  • Immune Health
  • Biological Age
  • Triglyceride Homeostasis
๐Ÿงช
Amino Acid Metabolism
7 key amino acid pathways
  • Arginine Metabolism
  • Lysine Metabolism
  • Threonine Metabolism
  • Tyrosine Metabolism
  • Tryptophan Metabolism
  • Phenylalanine Metabolism
  • Histidine Metabolism
โšก
Mitochondrial Pathways
Cardiac energy & cellular function
  • Cytokine Signalling
  • Mitochondrial Respiration Process
  • Energy Resistance

Unravelling Your Molecular Biochemistry

Three biological sources. One complete picture of your heart health.

We go beyond which microbes are present โ€” measuring and quantifying the downstream biochemical functions of your microbiome and mitochondria to decode the actual molecular mechanisms driving your cardiovascular risk.

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Gut Microbiome
The ecosystem of microbes in the large intestine. Gut microbiome-derived metabolites play a pivotal role in regulating arterial inflammation, lipid metabolism and endothelial function โ€” all central to cardiovascular disease onset.
Biochemical functions, not microbial diversity โ–พ
We go beyond microbial DNA and measure downstream functions performed by bacteria, fungi, viruses, phages and yeast living in your gut. Our analysis covers 400+ biological pathways encompassing 10,000+ biochemical functions. We categorise microbes by whether they are performing harmful or beneficial activities โ€” not as simply good or bad.
400+ Pathways Functional Analysis
๐Ÿฆท
Oral Microbiome
The most dense microbiome ecosystem in the body. Emerging evidence confirms the oral microbiome plays a direct role in cardiovascular health โ€” gum disease is a critical and often overlooked driver of arterial inflammation and heart disease.
How gum disease drives heart disease โ–พ
Imbalanced oral microbiome leads to biofilm and plaque formation โ€” pathogens secrete toxic byproducts into the bloodstream, causing systemic inflammation and directly contributing to atherosclerosis. VASCOMATH measures these oral microbial pathways to identify cardiovascular risk early and deliver targeted interventions.
ORAHYG PRO VASCOMATH
โšก
Mitochondrial Function
Mitochondrial efficiency is central to cardiovascular health. Dysfunctional mitochondria impair cellular energy production in cardiac tissue โ€” directly accelerating inflammation, arterial damage and heart disease progression.
How mitochondria impact heart health โ–พ
When mitochondria become dysfunctional due to ongoing inflammation and oxidative stress, ATP production declines and ROS production increases โ€” causing cellular damage in cardiac tissue and accelerating cardiovascular disease. We measure mitochondrial pathway scores and deliver biotherapeutics that restore cellular energy efficiency.
Energy Efficiency Cellular Health

Start Your Heart Health Journey

Fix your Health Health before your blood works show Abnormalities

Get your personalised cardiovascular risk score, understand the molecular pathways driving plaque deposition in your arteries, and receive precision interventions to prevent the onset of heart disease โ€” all from a simple at-home saliva sample.

Genefitletics

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